Class 12 Botany simulations · Molecular Basis of Inheritance

Transcription and translation

Transcribe a short gene into mRNA and translate it codon by codon. Then make a point mutation and see its effect.

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What to notice

A single base change can be silent, change one amino acid (missense) or create a stop codon (nonsense).

Key relation

DNA → mRNA (transcription) → protein (translation) ; AUG = start (Met)

Try this

Change codon 3 (AAA) to a stop codon by mutating one base.

What you can change

• Mutation position (0 = none): 0 to 18
• New base: choose A, T, G, C

More in Molecular Basis of Inheritance

• DNA double helix
• DNA fingerprinting with VNTRs
• The lac operon
• Semiconservative replication (Meselson–Stahl)

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