PHYSICA

Class 10 Zoology simulations · Control and Coordination

Thyroid feedback and iodine

Reduce dietary iodine. Less thyroid hormone is made, TSH rises by negative feedback and the thyroid enlarges (goitre).

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What to notice

Iodine deficiency causes hypothyroidism and enlargement of the thyroid gland (goitre).

Key relation

Hypothalamus (TRH) → pituitary (TSH) → thyroid (T₃, T₄) ⟲ negative feedback

Try this

Lower iodine intake below 50 μg/day. What happens to TSH and gland size?

What you can change

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